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The CSPCA Charitable Trust needs your support through donations to continue vital research projects. Your donation is tax deductible.
RASP (Rescue A Shar-Pei) is a volunteer group with a concern for abandoned and abused Shar-Pei in Illinois / Indiana / Wisconsin and surrounding areas.
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Health Issues
 AKC Canine Health Foundation Research Projects
The CSPCA Charitable Trust participates with the AKC Canine Health Foundation and other Parent Clubs in funding research projects which benefit dogs in
general. The CSPCA Charitable Trust also funds specific research projects on special interest to the Chinese Shar-Pei breed. These Projects are listed below:
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Dissecting the Biology and Genetics of c-Kit Mutations in Canine Mast Cell Tumors. Cheryl A. London, DVM, Ph. D. University of California, Davis.
Abstract: c-Kit is a gene which plays a critical role in regulating growth and function of normal mast cells. Mutations of the gene cause uncontrolled function of c-Kit and
likely influence mast cell tumor development in dogs. This research will investigate the role of c-Kit mutations on mast cells.
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Growth Singaling Pathways in the Pathogenesis and Treatment of Canine Cancer. Stuart C. Helfand, DVM, University of Wisconsin, Madison.
Abstract: This research is investigation the theory that loss of a tumor suppressor gene known as PTEN leads to increased production of tumor growth factors. Hemangiosarcoma is
the main focus in this project but the work applies to cancer across the board.
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The Molecular Cytogenetics of Canine Lymphosarcoma: Correlating Chromosomal Changes in Clinical Disease. Rober W. Dunstan, DVM, MS; Texas A ∓ M University, Matthew Breen,
PhD,; Animal Health Trust Great Britain.
Abstract: This research will use new reagents to identify chromosome abnormalities associated with dog lymphosarcoma and will attempt to sub-divide the types of lymphosarcoma.
This will offer new information of the diagnosis, prognosis and the therapy of lymphosarcoma.
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Mediodistal to Lateroproximal Radiographic View for Early Diagnosis of Fragmentation of the Medial Coronoid Process in Dogs. Denis J. Marcellin-Little, DEDV; North Carolina State
University.
Abstract: This project will test the utility of a novel, simple method to make radiographs of the elbow joint which will allow early detection of bone chips in the elbow joint
which often indicates the presence of elbow dysplasia.
- Development of DNA Markers for Shar-Pei Fever. Gary Johnson, DVM,
PhD.; University of Missouri, Columbia.
Abstract: The long-range objective of this project is to identify a
DNA marker that can facilitate the identification of carriers of Shar-Pei Fever.
Contribution to the AKC Canine Health Foundation can be made to:
AKC Canine Health Foundation
251 W. Garfield Rd., Suite 160
Aurora, Ohio 44202-8856
Telephone: 330-995-0807
Fax: 330 995-0806
E-Mail:akcchf@aol.com
Web:www.akcchf.org
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